CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo.
Studies in malaria patients Stereo Headphones indicate that higher frequencies of peripheral blood CD4(+) Foxp3(+) CD25(+) regulatory T (Treg) cells correlate with increased blood parasitemia.This observation implies that Treg cells impair pathogen clearance and thus may be detrimental to the host during infection.In C57BL/6 mice infected with Plas